Tocilizumab in Treatment for Patients With COVID-19

نویسندگان

چکیده

Shruti Gupta, MD, MPH; Wei Wang, PhD; Salim S. Hayek, MD; Lili Chan, MSCR; Kusum Mathews, MPH, Michal L. Melamed, MHS; Samantha K. Brenner, Amanda Leonberg-Yoo, MS; Edward J. Schenck, Jared Radbel, Jochen Reiser, Anip Bansal, Anand Srivastava, Yan Zhou, Diana Finkel, DO; Adam Green, MBA; Mary Mallappallil, Anthony Faugno, Jingjing Zhang, Juan Carlos Q. Velez, Shahzad Shaefi, Chirag R. Parikh, David M. Charytan, MSc; Ambarish Athavale, MBBS, Allon N. Friedman, Roberta E. Redfern, Samuel A. P. Short, BA; Simon Correa, MMSc; Kapil Pokharel, MBBS; Andrew Admon, John Donnelly, Hayley B. Gershengorn, Douin, Matthew W. Semler, Miguel Hernán, DrPH; Leaf, STOP-COVID Investigators; Carl Walther; Samaya Anumudu; Justin Arunthamakun; Kathleen F. Kopecky; Gregory Milligan; Peter McCullough; Thuy-Duyen Nguyen; Shaefi; Megan Krajewski; Sidharth Shankar; Ameeka Pannu; D. Valencia; Sushrut Waikar; Zoe Kibbelaar; Athavale; Hart; Shristi Upadhyay; Ishaan Vohra; Ajiboye Oyintayo; Green; Jean-Sebastien Rachoin; Christa Schorr; Lisa Shea; Daniel Edmonston; Christopher Mosher; Alexandre Shehata; Zaza Cohen; Valerie Allusson; Gabriela Bambrick-Santoyo; Noor ul aain Bhatti; Bijal Mehta; Aquino Williams; Brenner; Patricia Walters; Ronaldo C. Go; Keith Rose; Hernán; Rebecca Lisk; Amy Zhou; Ethan Kim; Chan; Mathews; Steven G. Coca; Deena Altman; Aparna Saha; Howard Soh; Huei Hsun Wen; Sonali Bose; Emily Leven; Jing Wang; Gohar Mosoyan; Girish Nadkarni; Pattharawin Pattharanitima; Gallagher; Friedman; Guirguis; Rajat Kapoor; Meshberger; Katherine Kelly; Parikh; Brian T. Garibaldi; Celia Corona-Villalobos; Yumeng Menez; Rubab Malik; Carmen Elena Cervantes; Samir Gautam; Mallappallil; Jie Ouyang; Sabu John; Ernie Yap; Yohannes Melaku; Ibrahim Mohamed; Siddhartha Bajracharya; Isha Puri; Mariah Thaxton; Jyotsna Bhattacharya; Wagner; Leon Boudourakis; H. Bryant Afshin Ahoubim; Kianoush Kashani; Shahrzad Tehranian; Leslie Thomas; Dheeraj Reddy Sirganagari; Pramod Guru; Paul Bergl; Jesus Rodriguez; Jatan Shah; Mrigank Gupta; Princy Kumar; Deepa Lazarous; Seble Kassaye; Melamed; Tanya Johns; Ryan Mocerino; Kalyan Prudhvi; Denzel Zhu; V. Levy; Yorg Azzi; Molly Fisher; Milagros Yunes; Kaltrina Sedaliu; Ladan Golestaneh; Maureen Brogan; Neelja Michael Chang; Jyotsana Thakkar; Ritesh Raichoudhury; Akshay Athreya; Mohamed Farag; Schenck; Soo Jung Cho; Maria Plataki; Sergio Alvarez-Mulett; Luis Gomez-Escobar; Di Pan; Stefi Lee; Jamuna Krishnan; William Whalen; Charytan; Ashley Macina; Sobaata Chaudhry; Benjamin Wu; Frank Modersitzki; Srivastava; Alexander Leidner; Martinez; Jacqueline Kruser; Richard Wunderink; Hodakowski; Velez; Eboni Price-Haywood; Matute-Trochez; Anna Hasty; Muner MB. Rupali Avasare; Zonies; Leaf; Meghan Sise; Erik Newman; Samah Abu Omar; Pokharel; Shreyak Sharma; Harkarandeep Singh; Correa; Tanveer Shaukat; Omer Kamal; Heather Yang; Jeffery O. Boateng; Ian Strohbehn; Jiahua Li; Ariel Mueller; Redfern; Nicholas Cairl; Gabriel Naimy; Abeer Abu-Saif; Danyell Hall; Laura Bickley; Chris Rowan; Farah Madhani-Lovely; Vasil Peev; Reiser; Byun; Vissing; Esha Kapania; Post; Nilam Patel; Joy-Marie Hermes; Anne Sutherland; Amee Patrawalla; Finkel; Barbara Danek; Sowminya Arikapudi; Jeffrey Paer; Cangialosi; Mark Liotta; Radbel; Sonika Jag Sunderram; Scharf; Ayesha Ahmed; Ilya Berim; Jayanth Vatson; Shuchi Anand; Joseph Levitt; Pablo Garcia; Suzanne Boyle; Rui Song; Ali Arif; Zhang; Sang Hoon Woo; Xiaoying Deng; Goni Katz-Greenberg; Katharine Senter; Moh’d Sharshir; Vadym Rusnak; Muhammad Imran Ali; Terri Peters; Kathy Hughes; Bansal; Amber Podoll; Michel Chonchol; Sunita Ellen Burnham; Douin; Arash Rashidi; Rana Hejal; Eric Judd; Latta; Ashita Tolwani; Timothy Albertson; Jason Y. Adams; Beutler; Schulze; Etienne Macedo; Harin Rhee; Liu; Vasantha Jotwani; Jay Koyner; Chintan Vishal Jaikaransingh; Stephanie Toth-Manikowski; Min Joo; James Lash; Javier Neyra; Nourhan Chaaban; Madona Elias; Yahya Ahmad; Alfredo Iardino; Elizabeth Au; Jill Marie Sosa; Sabrina Taldone; Contreras; De La Zerda; Alessia Fornoni; Gershengorn; Hayek; Pennelope Blakely; Hanna Berlin; Tariq U. Azam; Husam Shadid; Patrick O’ Hayer; Chelsea Meloche; Rafey Feroze; Kishan Padalia; Abbas Bitar; Jeff Leya; Donnelly; Admon; Jennifer Flythe; Tugman; Brent Brown; Leonberg-Yoo; Spiardi; Todd Miano; Meaghan Roche; Charles Vasquez; Amar Natalie Ernecoff; Sanjana Siddharth Verma; Huiwen Chen; Csaba Kovesdy; Miklos Z. Molnar; Ambreen Azhar; Susan Hedayati; Mridula Nadamuni; Shani Shastri; Duwayne Willett; A.P. Short; Renaghan; Kyle Enfield; Pavan Bhatraju; Bilal Semler; Anitha Vijayan; Christina Mariyam Joy; Tingting Seth Goldberg; Kao; Greg Schumaker; Nitender Goyal; Faugno; Caroline Hsu; Asma Tariq; Leah Meyer; Ravi Kshirsagar; Aju Jose; Weiner; Marta Christov; Griffiths; Sanjeev Aromma Perry Wilson; Tanima Arora; Ugochukwu Ugwuowo

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Efficacy of Tocilizumab in Patients with COVID-19

 Background and purpose: Tocilizumab (TCZ), a monoclonal antibody against interleukin-6 (IL-6) receptor, is emerged as an alternative treatment for COVID-19 patients with a risk of cytokine storms. This study aimed at investigating the efficacy of TCZ in patients with COVID-19. Materials and methods: In a retrospective observational study, we examined the demographic and clinical characteristi...

متن کامل

Treatment adherence in chronic patients during the Covid-19 pandemic

Introduction: The spread of the  (COVI-19) pandemic caused the creation of medical services and attention in health care, especially for patients with chronic diseases. Therefore, this study was conducted with the aim of determining adherence to treatment in chronic patients during daily covid-19. Materials and methods: In this cross-sectional study, 214 cases of people suffering from chronic d...

متن کامل

Prone Position Effects in the Treatment of Covid-19 Patients

Prone positioning is a conventional method to enhance oxygenation in Acute Respiratory Distress Syndrome (ARDS) patients who need mechanical ventilator . It is proven that oxygenation is significantly more beneficial in prone position compared to the supine position. Furthermore, numerous evidences have confirmed that prone positioning could prevent lung injuries caused by ventilators

متن کامل

The Effect of Intravenous Tocilizumab Therapy on the Prognosis of Patients with Covid-19: A Case-control Study

Background and Objective: Tocilizumab is a monoclonal antibody against the Interleukin-6 (IL6) receptor, but its effect on improving the clinical condition of coronavirus disease of 2019 (COVID-19) patients is debated. Accordingly, this study investigated the impact of Tocilizumab as an alternative treatment on the outcomes of covid-19 patients. Methods: In this retrospective case-control stud...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: JAMA Internal Medicine

سال: 2021

ISSN: ['2168-6114', '2168-6106']

DOI: https://doi.org/10.1001/jamainternmed.2021.0401